India's Premier AI CRO • Fortem Biosciences • Bangalore•4 Years of Deeptech Maturation

Engineering Next-Generation Therapeutics at Computational Scale.

India's premier AI-native Contract Research Organization. We engineer predictive deep learning architectures - DiscoveraAI, ReviveAI, and Enformis - to compress preclinical discovery, target validation, and solid-state formulation from years to under 72 hours.

Zero Trust Architecture
NVIDIA Inception Compute
AlphaFold 2 & OmegaFold
FDA 21 CFR 320/314 Ready
BACKED & RECOGNIZED BY PREMIER INSTITUTIONAL, TECHNOLOGY & ACADEMIC PARTNERS

Accelerated by global compute providers, premier state bio-incubators, and translational academic grants.

GPU Compute
NVIDIAINCEPTION
NVIDIAGPU Acceleration & Tensor Compute
Cloud Enclave
awsactivatePORTFOLIO
Amazon Web ServicesSecure Cloud & HIPAA Enclaves
Govt. Partner
STARTUPKARNATAKA
Startup KarnatakaState Innovation Council
Foundation Grant
WADHWANIFOUNDATION
Wadhwani FoundationDeeptech Entrepreneurship
Academic Co-R&D
WOXSENUNIVERSITY
Woxsen UniversityAcademic Research Alliance
Fintech Alliance
RazorpayRIZE
RazorpayEnterprise Financial Infrastructure
Wet-Lab Incubator
SKB BIOINCUBATOR
SKB Bio-IncubatorTranslational Bio-Incubator
DPIIT Recognized
#startupindiaDPIIT RECOGNIZED
#startupindiaNational Startup Recognition
GPU Compute
NVIDIAINCEPTION
NVIDIAGPU Acceleration & Tensor Compute
Cloud Enclave
awsactivatePORTFOLIO
Amazon Web ServicesSecure Cloud & HIPAA Enclaves
Govt. Partner
STARTUPKARNATAKA
Startup KarnatakaState Innovation Council
Foundation Grant
WADHWANIFOUNDATION
Wadhwani FoundationDeeptech Entrepreneurship
Academic Co-R&D
WOXSENUNIVERSITY
Woxsen UniversityAcademic Research Alliance
Fintech Alliance
RazorpayRIZE
RazorpayEnterprise Financial Infrastructure
Wet-Lab Incubator
SKB BIOINCUBATOR
SKB Bio-IncubatorTranslational Bio-Incubator
DPIIT Recognized
#startupindiaDPIIT RECOGNIZED
#startupindiaNational Startup Recognition
Maturity Milestone
Four Years of Relentless Scientific & Computational Validation
Empirically Benchmarkable • Production Ready
PHASE 1
4 Years
Mature Production AI Pipeline
Founded 2022 • Fortem Biosciences
PHASE 2
90%
Faster Preclinical Timelines
Target to Lead in Months vs. Years
PHASE 3
1.8M+
Interactome Graph Nodes
42M+ Relational Biological Edges
PHASE 4
100+
Zero Trust Datasets
HIPAA Isolated & 21 CFR Compliant
The Tri-Modal Platform

Three Synergistic Deeptech Pillars

From target to approved drug product: Ultraceuticals links de novo generative chemistry, knowledge-graph repurposing, and deep-learning solid-state formulation under Zero Trust Architecture.

PILLAR 01 • DE NOVO DISCOVERY

DiscoveraAI™

De Novo Preclinical Discovery (DTPred, DockAI, AlphaFold/OmegaFold)

An integrated discovery environment that unifies structural, relational, and literature signals. From target identification with DTPred to high-confidence 3D protein structures via AlphaFold 2/OmegaFold and flexible molecular docking with DockAI.

DTPred AI
Target Discovery
AlphaFold 2
Structure Models
DrugSim & DockAI
Screening Suite
Up to 90%
Cycle Compression
Architectural Differentiators:
Modular architecture: deploy Docking, Target Prediction, or Protein Structure independently
Target-aware pocket-conditioned 3D ligand generation and SAScore verification
Dynamic protein flexibility and orthosteric/allosteric binding site prediction
Zero Trust Architecture with cryptographic evidence trails and audit logs
DiscoveraAI Pipeline Telemetry
INFERENCE CONFIRMED
Module: DockAI & DTPred AI Target Validation
PREDICTED DRUG-TARGET INTERACTION#DTP-841
Target:
Tyrosine Kinase Oncogenic Active Site (PDB: 7K59)PDB: 7K59
AlphaFold 2 pLDDT Confidence:
94.2High Reliability
Predicted Binding Free Energy (ΔG):
-11.4 kcal/mol(Kd = 0.82 nM)
SAScore:
2.18Readily Synthesizable
PAINS Filters:
0 ViolationsClean FTO
NVIDIA L4 Acceleration: 99.8%Target Validated • Zero False Positive Confirmation
ENTERPRISE PRODUCTION SOFTWARE

Live Computational Platforms & Real Dashboards

Not conceptual mockups. Direct screenshots from our operational deeptech interfaces actively deployed for de novo molecular design, interactome drug repurposing, and autonomous regulatory intelligence.

LIVE ENCLAVE ONLINE
DiscoveraAI™ Deeptech Suite Dashboard Screenshot
DE NOVO DISCOVERY & 3D DOCKING
High-Throughput De Novo Target Prediction, 3D Macromolecular Modeling & DockAI

DiscoveraAI™ Deeptech Suite

The flagship DiscoveraAI operational workbench directly captures real-time 3D PDB protein coordinates, computes Gibbs free energy (ΔG) via AutoDock Vina & DockAI, predicts ADMET pharmacokinetics, and optimizes pocket-conditioned ligands with zero false-positive filtering.

Live 3D WebGL PDB coordinate visualizer with interactive ribbon, mesh, and pocket docking
Deterministic SAScore synthesisability verification and automated PAINS filter enforcement
Integrated ADMET property profiling (blood-brain barrier, CYP450, hERG inhibition)
Zero Trust cryptographic session logging protecting proprietary lead matter
Active Telemetry & Verified Benchmarks
Target EngineDTPred AI Transformer
3D StructureAlphaFold 2 & OmegaFold
Docking SolverDockAI (ΔG = -11.4 kcal/mol)
AccelerationNVIDIA L4 Tensor Enclave
Real-time production cluster acceleration on Genesis Platform.
DiscoveraAI™ Deeptech Suite
DISCOVERA

DiscoveraAI™ Deeptech Suite

High-Throughput De Novo Target Prediction, 3D Macromolecular Modeling & DockAI

Active View
ReviveAI™ (SCALEX) Engine
REVIVE

ReviveAI™ (SCALEX) Engine

1.8 Million Nodes, 42M Biological Edges, Contrastive GNN Repurposing

Click to Inspect
Dossier360™ Intelligence Studio
DOSSIER

Dossier360™ Intelligence Studio

Autonomous Hatch-Waxman Patent Swarms & BCS Bioequivalence Invalidation

Click to Inspect
In Silico Biophysical Simulations

Real-Time Structural & Docking Dynamics

Moving beyond static crystallographic models. Our engines simulate induced-fit protein cavity flexibility, conformational search trajectories, and nucleic acid interactions in 60fps real-time.

Active Docking Dynamics (DockAI™)
Receptor Kinase Pocket (PDB: 7K59)
Conformational Ensemble SearchPredicted ΔG: -11.4 kcal/mol
Genomic Backbone & Nucleic Modeling60 FPS ACTIVE KINEMATICS
Biophysical Convergence

Atomic Forcefield Precision

Explicit solvent amber forcefield combined with QM/MM induced-fit sampling resolves allosteric binding grooves and calculates thermodynamic free energy (ΔG) with experimental-grade precision (±0.8 kcal/mol).

Preclinical Computational Pipeline

The End-to-End Discovery Architecture

From molecular data ingestion to clinical formulation insights. An integrated pipeline unifying Graph Neural Networks, Large Language Models, AlphaFold 2, and Zero Trust Architecture.

STAGE 01 / 06INFRASTRUCTURE

Zero Trust Data Ingestion

Core Engine: Zero Trust Architecture (ZTA)

All biological, genomic, proteomic, and clinical datasets are securely ingested under Zero Trust Architecture. Cryptographic access verification, role-based isolation (RBAC), and immutable audit logs guarantee full data provenance and regulatory compliance.

Validation Milestones:
Cryptographic data lineage & provenance tracking
Role-based access control (RBAC) with HIPAA air-gapping
Multi-omics phenotyping integration (Genomic, Transcriptomic, RWE)
Engine BenchmarkVERIFIED
Primary Metric:100+ Datasets Under ZTA
Security Standard:Zero Trust Architecture
Hardware Enclave:NVIDIA L4 Tensor Core
Compliance:FDA 21 CFR 320/314
Secure aggregation of biological, genomic, and clinical trial datasets.
Interactive Computational Workbench

Test-Drive the Research Engine

Execute real-time simulated neural inferences across our active therapeutic and regulatory pipelines.

ReviveAI™ (SCALEX) Node-Level Contrastive GNN

Assay 01: Phenotypic Microglial Repolarization (CHIT1 Target)

Input Parameters
Target Protein: Human Chitinase-1 (CHIT1) | Disease Model: Amyotrophic Lateral Sclerosis (ALS)
Target Binding Affinity (Kd)
1.2 nM (Sub-nanomolar)
Interactome Cosine Match
0.9412 (p < 10^-8)
Microglial M1 -> M2 Shift
+384% Anti-inflammatory
Toxicity / ADMET Profile
Class 4 (Clean Margin)
Inference Telemetry Stream
PROGRESS: 100%
>[0.00s] Ingesting Human Interactome heterogeneous graph (1.8M nodes, 42M edges)...
>[0.04s] Executing Node-Level Contrastive GNN inference over CHIT1 catalytic groove...
>[0.08s] Applying Modality Dropout Defense against single-cell transcriptomic noise...
>[0.12s] Validated Candidate: Scalex-ULTR-08 (Dual Chitinase / M2 repolarizer)...
>[0.14s] FTO analysis cleared under Indian, US, and European patent classifications.
Preclinical Repurposing Lead: Scalex-ULTR-08
Demonstrated >85% suppression of TNF-α and IL-1β in vitro; Phase IIa repurposing ready.
Institutional Evolution & Provenance

Four Years of Scientific Maturation

From founding algorithms to full-stack pharmaceutical intelligence. Fortem Biosciences has systematically de-risked every phase of the drug discovery, repurposing, and formulation lifecycle.

2022YEAR 01

Incorporation & 1.8M-Node Interactome Knowledge Graph

Fortem Biosciences Pvt. Ltd. was legally incorporated in Bengaluru in June 2022, co-founding ULTRACEUTICALS with an algorithmic mandate. Initiated the construction of the human interactome heterogeneous knowledge graph (1.8M nodes, 42M biological edges) for deeptech computational biology.

Empirical Metric: Incorporated June 2022 • 1.8M Interactome Nodes
2023YEAR 02

DiscoveraAI Discovery Engine & Peer-Reviewed Research

Launched DiscoveraAI generative chemistry and DynaDock microsecond molecular dynamics suite. Published peer-reviewed research in Nutrients (Aug 2023, 15(17):3751) on oat avenanthramides and PI3K signaling in neurodegeneration with international university collaborators.

Empirical Metric: Nutrients (2023) 15(17):3751 • DynaDock GPU MD
2024YEAR 03

ReviveAI (SCALEX) Repurposing & Second Peer-Reviewed Paper

Deployed ReviveAI (SCALEX) enterprise drug repurposing using node-level contrastive GNNs with modality dropout defense. Published peer-reviewed research in Life (Apr 2024, 14(4):504) validating tangeretin for neuroinflammation-mediated neurodegeneration with JSS AHER & Sejong University.

Empirical Metric: Life (2024) 14(4):504 • Validated in CHIT1 ALS
2025YEAR 04

Dossier360 Regulatory Swarms & Razorpay National Spotlight

Engineered Dossier360 multi-agent regulatory due-diligence intelligence for Orange/Purple book patent thicket triaging and bioequivalence risk automation. Featured nationally in Razorpay Rize's 'Backing India's Boldest' spotlight.

Empirical Metric: FDA 21 CFR 320/314 Ready • Razorpay Rize Spotlight
2026LATEST BREAKTHROUGH

Enformis CMC AI, Razorpay Next Big Thing & AI CRO Repositioning

Launched Enformis predictive solid-state formulation AI (Tonset ±3.8°C across 106 validated APIs). Featured in Razorpay's 'Next Big Thing' Sketchpad episode and Bengaluru billboard. Formally repositioned as an AI-first CRO services model with proprietary computational software kept internal.

Empirical Metric: 106 Validated APIs • Razorpay Next Big Thing • Full CRO Services
Academic Scientific Partnership

The UASPIRE Alliance Program

Partnering with universities, research institutions, and student fellows (Woxsen University, NIT Calicut, SKB Bio-incubator) to advance cutting-edge AI drug discovery and computational biology.

Explore UASPIRE Partnerships
Partner With Ultraceuticals

Accelerate Your Preclinical Discovery Program.

Whether you require de novo candidate generation, knowledge-graph drug repurposing, or preemptive formulation modeling - Fortem Biosciences delivers verified computational results.

Fortem Biosciences Pvt. Ltd. (Bengaluru, India)•Official Email: info@ultraceuticals.in•Zero Trust & HIPAA-Isolated